Recommended immunization schedules: Canadian Immunization Guide

This chapter has been updated with guidance from the Pneumococcal vaccines chapter and from the following statements from the National Advisory Committee on Immunization (NACI):

• March 11, 2024: Recommendations for public health programs on the use of pneumococcal vaccines in children, including the use of 15-valent and 20-valent conjugate vaccines
• March 21, 2023: Interim guidance on the use of pneumococcal 15-valent conjugate vaccine (PNEU-C-15) in pediatric populations
• February 24, 2023: Public health level recommendations on the use of pneumococcal vaccines in adults, including the use of 15-valent and 20-valent conjugate vaccines.

This information is captured in the table of updates.

Last complete chapter revision: December 2013

On this page

• General recommendations
• Table 1: Routine childhood immunization schedule, infants and children (birth to 17 years of age)
• Table 2: Recommended immunization schedule, children (less than 7 years of age), NOT Previously Immunized as Infants
• Table 3: Recommended immunization schedule, children (7 to 17 years of age), NOT Previously Immunized
• Table 4: Additional recommended immunizations, children (birth to 17 years of age), Considered AT RISK due to Underlying Medical Conditions
• Table 5: Recommended immunization schedule, adults (18 years of age and older), NOT Previously Immunized
• Table 6: Recommended immunizations, adults (18 years of age and older), Previously Immunized
• Table 7: Additional recommended immunizations, adults (18 years of age and older), Considered at risk

General recommendations

Administration of vaccines in accordance with the immunization schedules summarized in the following tables will provide optimal protection from vaccine preventable diseases for most individuals. However, modifications of the recommended schedule may be necessary due to missed appointments or illness. In general, interruption of an immunization series does not require restarting the vaccine series, regardless of the interval between doses. Individuals with interrupted immunization schedules should be vaccinated to complete the appropriate schedule for their current age. Refer to Timing of vaccine administration in Part 1 and vaccine-specific chapters in Part 4 for additional information.

Similar, but not identical, vaccines may be available from different manufacturers; therefore, it is useful to review the relevant vaccine-specific chapters in the Canadian Immunization Guide as well as the manufacturer's product leaflet or product monograph before administering a vaccine. Refer to Principles of vaccine interchangeability in Part 1 for information about the interchangeability of similar vaccines from different manufacturers. Product monographs are periodically updated; it is a best practice to consult the information contained within the product monographs available through Health Canada's Drug Product Database.

Table 1: Routine childhood immunization schedule, infants and children (birth to 17 years of age)

• For children at-risk due to underlying medical conditions, refer to Table 4 for additional recommendations for immunization.
• [ ] = dose(s) may not be required depending upon age of child or vaccine used or both (refer to the relevant vaccine-specific chapter in Part 4 and provincial/territorial schedule). mos = months. yrs = years. P/T = provincial and territorial.
• Refer to Timing of vaccine administration and Vaccine administration practices in Part 1 regarding administration of multiple injections.
• Refer to vaccine-specific chapters in Part 4 for additional information.

For abbreviations and brand names of vaccines refer to Contents of immunizing agents authorized for use in Canada in Part 1.

Table 1 - Footnote A

Diphtheria toxoid- tetanus toxoid- acellular pertussis- inactivated polio- Haemophilus influenzae type b (DTaP-IPV-Hib). For infants and children beginning primary immunization at 7 months of age and older, the number of doses of Hib vaccine required varies by age.

Table 1 - Footnote B

Diphtheria toxoid- tetanus toxoid- acellular pertussis- hepatitis B- inactivated polio- Haemophilus influenzae type b (DTaP-HB-IPV-Hib). Alternative schedules may be used : DTaP-HB-IPV-Hib at 2, 4 and 12-23 months of age with DTaP-IPV-Hib vaccine at 6 months of age; or DTaP-HB-IPV -Hib at 2, 4 and 6 months of age with DTaP-IPV-Hib vaccine at 12-23 months of age.

Table 1 - Footnote C

Table 1 - Footnote D

Table 1 - Footnote E

Rotavirus: Rotavirus pentavalent vaccine - 3 doses, 4 to 10 weeks apart; Rotavirus monovalent vaccine - 2 doses, at least 4 weeks apart. Give the first dose starting at 6 weeks and before 15 weeks of age. Administer all doses before 8 months of age.

Table 1 - Footnote F

Pneumococcal conjugate 15 or 20-valent (Pneu-C-15 or Pneu-C-20): infants without medical or environmental risk factors for invasive pneumococcal disease (IPD) beginning primary immunization at 2 to less than 7 months of age: 3 or 4 dose schedule. For a 3 dose schedule : 2, 4 months of age, followed by a booster dose at 12 to 15 months of age. For a 4 dose schedule: minimum of 8 weeks interval between doses beginning at 2 months of age, followed by a booster dose at 12 to 15 months of age. Infants without medical or environmental risk factors for IPD beginning primary immunization at 7 to less than 12 months of age: 2 doses, at least 8 weeks apart followed by a booster dose at 12 to 15 months of age, at least 8 weeks after the second dose.

Children without medical or environmental risk factors for IPD who have received age-appropriate pneumococcal vaccination with Pneu-C-13 vaccine do not need an additional dose of Pneu-C-15 or Pneu-C-20.

Table 1 - Footnote G

Meningococcal conjugate monovalent: children 12-48 months of age: 1 dose routinely provided at 12 months of age, regardless of any doses given during the first year of life. Immunization may be considered for unimmunized children 5-11 years of age.

Table 1 - Footnote H

Meningococcal conjugate monovalent or meningococcal conjugate quadrivalent: early adolescence (around 12 years of age) - 1 dose, even if meningococcal conjugate vaccine received at a younger age. Vaccine chosen depends on local epidemiology and programmatic considerations.

Table 1 - Footnote I

Measles-mumps-rubella: first dose at 12-15 months of age; second dose at 18 months of age or anytime thereafter, but should be given no later than around school entry.

Table 1 - Footnote J

Varicella (chickenpox): first dose at 12-15 months of age; second dose at 18 months of age or anytime thereafter, but should be given no later than around school entry.

Table 1 - Footnote K

Measles-mumps-rubella-varicella: first dose at 12-15 months of age; second dose at 18 months of age or anytime thereafter, but should be given no later than around school entry.

Table 1 - Footnote L

Hepatitis B : months 0, 1 and 6 (first dose = month 0) with at least 4 weeks between the first and second dose, at least 2 months between the second and third dose, and at least 4 months between the first and third dose. Alternatively, can be administered as DTaP-HB-IPV-Hib vaccine, with first dose at 2 months of age.

Table 1 - Footnote M

Hepatitis B: 9-17 years of age - months 0, 1 and 6 (first dose = month 0) with at least 4 weeks between the first and second dose, at least 2 months between the second and third dose, and at least 4 months between the first and third dose. 11-15 years of age - 2 doses; schedule depends on the product used.

Table 1 - Footnote N

Human papillomavirus (HPV): Girls, 9-14 years of age: HPV bivalent (HPV2) or HPV nonavalent (HPV9) vaccine - months 0 and 6-12 (first dose = month 0). Alternatively, a 3 dose schedule may be used for HPV2 vaccine - months 0, 1 and 6 (first dose = month 0) and for HPV nonavalent (HPV9) vaccine - months 0, 2 and 6 (first dose = month 0). Boys, 9-14 years of age: HPV9 vaccine - months 0 and 6-12 (first dose = month 0). Alternatively, a 3 dose schedule may be used for HPV9 vaccine - months 0, 2 and 6 (first dose = month 0). For a 2 or 3 dose schedule, the minimum interval between first and last doses is 6 months.

Table 1 - Footnote O

Human papillomavirus: Girls, 15-17 years of age: HPV2 vaccine - months 0, 1 and 6 (first dose = month 0) or HPV9 vaccine - months 0, 2 and 6 (first dose = month 0). Boys, 15-17 years of age: HPV9 vaccine - months 0, 2 and 6 (first dose = month 0). In individuals who received the first dose of an HPV vaccine between 9-14 years of age, a 2 dose schedule can be used with the second dose administered at least 6 months after the first dose.

Table 1 - Footnote P

Influenza: recommended annually for anyone 6 months of age and older without contraindications. Children 6 months-less than 9 years of age, receiving influenza vaccine for the first time - 2 doses, at least 4 weeks apart. Children 6 months-8 years of age, previously immunized with influenza vaccine and children 9 years of age and older - 1 dose.

Table 2: Recommended Immunization Schedule, Children (less than 7 years of age), NOT Previously Immunized as Infants

• For children at-risk due to underlying medical conditions, refer to Table 4 for additional recommendations for immunization.
• [ ] = dose(s) may not be required depending upon age of child or vaccine used or both (refer to the relevant vaccine-specific chapter in Part 4 and provincial/territorial schedule). mos = months.
• Refer to Timing of vaccine administration and Vaccine administration practices in Part 1 regarding administration of multiple injections.
• Refer to vaccine-specific chapters in Part 4 for additional information.

For abbreviations and brand names of vaccines refer to Contents of Immunizing agents authorized for use in Canada in Part 1.

Table 2 - Footnote A

Diphtheria toxoid- tetanus toxoid- acellular pertussis- inactivated polio- Haemophilus influenzae type b (DTaP-IPV-Hib) or diphtheria toxoid- tetanus toxoid- acellular pertussis- inactivated polio (DTaP-IPV): 4 doses of DTaP-IPV-containing vaccine. The number of doses of Hib-containing vaccine required varies by age at first dose. If first visit at 12-14 months of age: 1 dose of Hib-containing vaccine at first visit and booster dose at least 2 months after the previous dose. If first visit at 15 months-less than 60 months of age: 1 dose of Hib-containing vaccine. If first visit at 60 months of age or older, Hib-containing vaccine is not required.

Table 2 - Footnote B

Diphtheria toxoid- tetanus toxoid- acellular pertussis- inactivated polio (DTaP-IPV) or tetanus toxoid- reduced diphtheria toxoid- reduced acellular pertussis- inactivated polio (Tdap-IPV): if the fourth dose of DTaP-IPV vaccine was given before the fourth birthday, a booster dose of DTaP-IPV or Tdap-IPV vaccine should be provided at 4-6 years of age.

Table 2 - Footnote C

Pneumococcal conjugate 15 or 20-valent: For children without medical or environmental IPD risk factors, 12 to less than 24 months of age - 2 doses, at least 8 weeks apart. 24 to less than 60 months of age - 1 dose.

Table 2 - Footnote D

Meningococcal conjugate monovalent: 12-59 months of age - 1 dose; 5-11 years of age - consider 1 dose.

Table 2 - Footnote E

Measles-mumps-rubella: 2 doses, at least 4 weeks apart; second dose after 18 months of age, but should be given no later than around school entry.

Table 2 - Footnote F

Varicella: 2 doses, at least 3 months apart; second dose after 18 months of age, but should be given no later than around school entry. A minimum interval of 4 weeks between doses may be used if rapid, complete protection is required.

Table 2 - Footnote G

Measles-mumps-rubella-varicella: 2 doses, at least 3 months apart; second dose after 18 months of age, but should be given no later than around school entry. A minimum interval of 4 weeks between doses may be used if rapid, complete protection is required.

Table 2 - Footnote H

Hepatitis B: 3 doses - months 0, 1 and 6 (first dose = month 0) with at least 4 weeks between the first and second dose, 2 months between the second and third dose, and 4 months between the first and third dose.

Table 2 - Footnote I

Influenza: 2 doses, at least 4 weeks apart.

Table 3: Recommended immunization schedule, children (7 to 17 years of age), not previously immunized

• For children at-risk due to underlying medical conditions, refer to Table 4 for additional recommendations for immunization.
• [ ] = dose(s) may not be required depending upon age of child or vaccine used or both (refer to the relevant vaccine-specific chapter in Part 4 and provincial/territorial schedule). mos = months. yrs = years.
• Refer to Timing of vaccine administration and Vaccine administration practices in Part 1 regarding administration of multiple injections.
• Refer to the vaccine-specific chapters in Part 4 for additional information.

For abbreviations and brand names of vaccines refer to Contents of immunizing agents authorized for use in Canada in Part 1.

Table 3 - Footnote A

Tetanus toxoid- reduced diphtheria toxoid- reduced acellular pertussis- inactivated polio (Tdap-IPV): 2 doses, 8 weeks apart; third dose 6-12 months after second dose.

Table 3 - Footnote B

Tetanus toxoid- reduced diphtheria toxoid- reduced acellular pertussis: 10 years after last dose of Tdap-IPV.

Table 3 - Footnote C

Meningococcal conjugate monovalent: 7-11 years of age - consider 1 dose.

Table 3 - Footnote D

Meningococcal conjugate monovalent or quadrivalent: 12-17 years of age - 1 dose, even if meningococcal conjugate vaccine received at a younger age. Vaccine chosen depends on local epidemiology and programmatic considerations.

Table 3 - Footnote E

Measles-mumps-rubella: 2 doses, at least 4 weeks apart.

Table 3 - Footnote F

Varicella (chickenpox): 7-12 years of age - 2 doses, at least 3 months apart. 13 years of age and older - 2 doses, at least 6 weeks apart. A minimum interval of 4 weeks between doses may be used if rapid, complete protection is required.

Table 3 - Footnote G

Measles-mumps-rubella-varicella: 7-12 years of age - 2 doses, at least 3 months apart. A minimum interval of 4 weeks between doses may be used if rapid, complete protection is required.

Table 3 - Footnote H

Hepatitis B: 7-17 years of age - 3 doses, months 0, 1 and 6 (first dose = month 0) with at least 4 weeks between the first and second dose, 2 months between the second and third dose, and 4 months between the first and third dose. 11-15 years of age - two doses; schedule depends on the product used.

Table 3 - Footnote I

Human papillomavirus (HPV): Girls, 9-14 years of age - HPV bivalent (HPV2) or HPV nonavalent (HPV9) - months 0 and 6-12 (first dose = month 0). Alternatively, a 3 dose schedule may be used for HPV2 vaccine - months 0, 1 and 6 (first dose = month 0) and for HPV nonavalent (HPV9) vaccine - months 0, 2 and 6 (first dose = month 0). Boys, 9-14 years of age HPV9 - months 0 and 6-12 (first dose = month 0). Alternatively, a 3 dose schedule may be used for HPV9 vaccine - months 0, 2 and 6 (first dose = month 0). For a 2 or 3 dose schedule, the minimum interval between first and last doses is 6 months.

Table 3 - Footnote J

Human papillomavirus: Girls, 15-17 years of age: HPV2 vaccine - months 0, 1 and 6 (first dose = month 0) or HPV9 vaccine - months 0, 2 and 6 (first dose = month 0). Boys, 15-17 years of age: HPV9 vaccine - months 0, 2 and 6 (first dose = month 0). In individuals who received the first dose of an HPV vaccine between 9-14 years of age, a 2 dose schedule can be used with the second dose administered at least 6 months after the first dose.

Table 3 - Footnote K

Influenza: children less than 9 years of age - 2 doses, at least 4 weeks apart. Children 9 years of age and older - 1 dose.

Table 4: Additional recommended immunizations, children (birth to 17 years of age), considered at risk due to underlying medical conditions

• [ ] = dose(s) may not be required depending upon age of child or vaccine used or both (refer to vaccine-specific chapter in Part 4 and provincial/territorial schedule). mos = months. yrs = years.
• Refer to Immunization of travellers and Immunization of workers in Part 3 for additional information about vaccines recommended for travellers and workers.
• Refer to Immunization of immunocompromised persons and Immunization of persons with chronic diseases in Part 3 for additional condition-specific recommendations.
• Refer to Timing of vaccine administration and Vaccine administration practices in Part 1 regarding administration of multiple injections.
• Refer to the vaccine-specific chapters in Part 4 for additional information

For abbreviations and brand names of vaccines refer to Contents of immunizing agents authorized for use in Canada in Part 1.

Table 4 - Footnote A

Haemophilus influenzae type b (Hib): 5 years of age and older with increased risk of invasive Hib disease - 1 dose regardless of prior history of Hib vaccination and at least 1 year after any previous dose.

Table 4 - Footnote B

Pneumococcal conjugate 20-valent: infants at high risk of IPD due to a medical, environmental or living condition - a 4-dose schedule at 2, 4, and 6 months followed by a dose at 12 to 15 months of age. The minimum interval between doses is 8 weeks. Unimmunized infants presenting for vaccination at 7 to less than 12 months of age should receive 2 doses of Pneu-C-20 vaccine at least 8 weeks apart followed by a third dose at 12 to 15 months of age, at least 8 weeks after the second dose. Infants with an interrupted or incomplete schedule who are less than 12 months of age should complete their immunization schedule as if no interruption had occurred. If pneumococcal vaccine series started with Pneu-C-13 or Pneu-C-15, give Pneu-C-20 vaccine to complete series. Children two years of age and older who are at increased risk of IPD and have never received any pneumococcal vaccination, should receive 1 dose of Pneu-C-20.

Table 4 - Footnote C

Meningococcal conjugate quadrivalent (Men-C-ACYW): infants and children at high risk of invasive meningococcal disease (IMD): 2-11 months of age - 2 or 3 doses of Men-C-ACYW-CRM vaccine, 8 weeks apart with another dose between 12-23 months of age and at least 8 weeks after the previous dose; 12-23 months of age - 2 doses of Men-C-ACYW-CRM vaccine,8 weeks apart; 24 months of age and older - 2 doses of any Men-C-ACYW vaccine, 8 weeks apart. Give additional booster doses every 3 to 5 years if last vaccinated at 6 years of age and younger and every 5 years if last vaccinated at 7 years of age and older.

Table 4 - Footnote D

Multicomponent meningococcal (4CMenB): infants and children at high risk of IMD should be considered for immunization: 2-11 months of age - 2 or 3 doses of 4CMenB vaccine, 8 weeks apart with another dose between 12-23 months of age and at least 8 weeks after the previous dose; 1-10 years of age- 2 doses of 4CMenB vaccine, 8 weeks apart; 11 years of age and older - 2 doses of 4CMenB vaccine, at least 4 weeks apart. The need for and timing of 4CMenB vaccine booster doses have not yet been determined.

Table 4 - Footnote E

Hepatitis A: 6 months of age and older in high-risk groups: 2 doses, given 6-36 months apart (depending on product used).

Table 4 - Footnote F

Hepatitis B: 3 or 4 doses of higher dose of monovalent hepatitis B vaccine recommended for those with certain immunocompromising conditions, chronic renal failure and dialysis. Premature infants weighing less than 2,000 grams at birth born to HB infected mothers: 4 doses.

Table 4 - Footnote G

Influenza: recommended annually for all individuals 6 months of age and older without contraindications, with focus on children at risk of influenza-related complications. Children 6 months-less than 9 years of age receiving influenza vaccine for the first time: 2 doses, at least 4 weeks apart. Children 6 months-8 years of age, previously immunized with influenza vaccine and children 9 years of age and older: 1 dose.

Table 5: Recommended immunization schedule, adults (18 years of age and older), not previously immunized

• For adults considered at-risk, refer to Table 7 for additional recommendations for immunization.
• [ ] = dose(s) may not be required depending upon age of vaccinee or vaccine used or both (refer to vaccine-specific chapter in Part 4 and provincial/territorial schedule). mos = months.
• Refer to Immunization of travellers and Immunization of workers in Part 3 for additional information about vaccines recommended for travellers and workers.
• Refer to Timing of vaccine vdministration and Vaccine vdministration practices in Part 1 regarding administration of multiple injections.
• Refer to vaccine-specific chapters in Part 4 for further information.

For abbreviations and brand names of vaccines refer to Contents of immunizing agents authorized for use in Canada in Part 1.

Table 5 - Footnote A

Three doses of either tetanus toxoid- reduced diphtheria (Td, if not previously immunized with tetanus or diphtheria), or polio-containing vaccine if at increased risk of polio (Tdap-IPV, if not previously immunized with tetanus, diphtheria and polio, or IPV, if not previously immunized with polio) provided with an interval of 8 weeks between the first two doses followed by a third dose administered 6 to 12 months after the second dose. One dose of reduced acellular pertussis-containing vaccine should be provided to those who never previously received a pertussis-containing vaccine in adulthood.
Adults who are unimmunized against polio but are not at increased risk and have had a primary series of tetanus and diphtheria containing vaccine, should receive IPV-containing vaccine as a part of their next tetanus and diphtheria booster.

Table 5 - Footnote B

Tetanus toxoid- reduced diphtheria toxoid (Td): 10 years after last dose of Td-containing vaccine.

Table 5 - Footnote C

Measles-mumps-rubella (MMR): adults born in or after 1970 - 1 dose, except - travellers, health care workers, students in post-secondary educational settings, and military personnel - 2 doses, at least 4 weeks apart. Adults born before 1970 can be presumed to have acquired natural immunity to measles and mumps and do not need MMR vaccination except - non-immune military personnel or health care workers (2 doses, at least 4 weeks apart), non-immune travellers (1 dose), non-immune students in post-secondary educational settings (consider 1 dose). Rubella-susceptible adults, regardless of age - 1 dose.

Table 5 - Footnote D

Varicella (chickenpox): adults 18 to 49 years of age - 2 doses, at least 6 weeks apart; adults 50 years of age and older are generally presumed to be immune.

Table 5 - Footnote E

Recombinant Zoster Vaccine (RZV): adults 50 years of age and older - 2 doses, 2 to 6 months apart; may be considered for immunocompromised adults 50 years of age and older based on a case-by-case assessment of benefits vs risks.

Table 5 - Footnote F

Pneumococcal conjugate 20-valent: adults 65 years of age and older - 1 dose; immunization with Pneu-C-15 followed by Pneu-P-23 may be offered as an alternative to Pneu-C-20.

Table 5 - Footnote G

Meningococcal conjugate monovalent or quadrivalent: adults less than 25 years of age - 1 dose (vaccine chosen depends on local epidemiology).

Table 5 - Footnote H

Human papillomavirus (HPV): recommended for women up to and including 26 years of age, may be given to women 27 years of age and older at ongoing risk of exposure: HPV bivalent (HPV2) vaccine - months 0, 1 and 6 (first dose = month 0) or nonavalent (HPV9) vaccine- months 0, 2 and 6 (first dose = month 0). Recommended for men up to and including 26 years of age, may be given to men 27 years of age and older at ongoing risk of exposure: HPV9 vaccine - months 0, 2 and 6 (first dose = month 0).

Table 5 - Footnote I

Influenza: 1 dose recommended for adults without contraindications, with focus on: adults at high risk of influenza-related complications (including pregnant women, adults 65 years of age and older); adults capable of transmitting influenza to individuals at high risk; adults who provide essential community services; and people in direct contact during culling operations with poultry infected with avian influenza.

Table 6: Recommended immunizations, adults (18 years of age and older), previously immunized

• For adults considered at-risk, refer to Table 7 for additional recommendations for immunization.
• [] = dose may not be required.
• Refer to Immunization of travellers and Immunization of workers in Part 3 for additional information about vaccines recommended for travellers and workers.
• Refer to Timing of vaccine administration and Vaccine administration practices in Part 1 regarding administration of multiple injections.
• Refer to vaccine-specific chapters in Part 4 for additional information.

For abbreviations and brand names of vaccines refer to Contents of immunizing agents authorized for use in Canada in Part 1.

Table 6 - Footnote A

Tetanus toxoid- reduced diphtheria toxoid: 1 booster dose every 10 years.

Table 6 - Footnote B

Tetanus toxoid- reduced diphtheria toxoid- reduced acellular pertussis (Tdap): 1 dose in adulthood for pertussis protection regardless of interval since last dose of tetanus toxoid- and diphtheria toxoid-containing vaccine; 1 dose in every pregnancy, ideally between 27 and 32 weeks of gestation, for pertussis protection of infants. Refer to Pertussis vaccine in Part 4 for additional information.

Table 6 - Footnote C

Pneumococcal conjugate 20-valent: Regardless of Pneu-C-13 or Pneu-P-23 vaccination status, 1 dose of Pneu-C-20 is recommended for all adults 65 years of age and older - 1 dose at least 1 year from either the last Pneu-C-13 dose or the last Pneu-P-23 dose.

Table 6 - Footnote D

Recombinant Zoster Vaccine (RZV): adults 50 years of age and older - 2 doses, 2 to 6 months apart and at least 1 year after LZV.

Table 6 - Footnote E

Influenza: recommended for all adults without contraindications, with focus on: adults at high risk of influenza-related complications (including pregnant women, adults 65 years of age and older); adults capable of transmitting influenza to individuals at high risk; adults who provide essential community services; and people in direct contact during culling operations with poultry infected with avian influenza. One dose annually.

Table 7: Additional recommended immunizations, adults (18 years of age and older), considered at risk

• Refer to Immunization of travellers and Immunization of workers in Part 3 for information about vaccines recommended for travellers and workers.
• Refer to Immunization of immunocompromised persons and Immunization of persons with chronic diseases in Part 3 for additional condition-specific immunization recommendations.
• Refer to Timing of vaccine administration and Vaccine administration practices in Part 1 regarding administration of multiple injections.
• Refer to vaccine-specific chapters in Part 4 for additional information.

List is not exhaustive of travel vaccines. For abbreviations and brand names of vaccines refer to Contents of immunizing agents authorized for use in Canada in Part 1.

Table 7 - Footnote A

Haemophilus influenzae type b (Hib): adults with increased risk of invasive Hib disease - 1 dose regardless of prior history of Hib vaccination and at least 1 year after any previous dose.

Table 7 - Footnote B

Inactivated polio: 1 booster dose for adults at increased risk of exposure to polio.

Table 7 - Footnote C

Measles-mumps-rubella (MMR): adults born in or after 1970 - 1 dose, except - travellers, health care workers, students in post-secondary educational settings, and military personnel - 2 doses, at least 4 weeks apart. Adults born before 1970 can be assumed to have acquired natural immunity to measles and mumps and do not need MMR vaccination except - non-immune military personnel or health care workers (2 doses, at least 4 weeks apart), non-immune travellers (1 dose), non-immune students in post-secondary educational settings (consider 1 dose). Rubella-susceptible adults, regardless of age - 1 dose.

Table 7 - Footnote D

Pneumococcal conjugate 20-valent (Pneu-C-20): all adults with medical or environmental conditions that result in an increased risk of IPD: Immunodeficiencies; immunocompromising therapy, HIV infection, hematopoietic stem cell transplant (recipient), malignant neoplasms, solid organ or islet transplant (recipient), chronic kidney or liver, disease, asplenia or splenic dysfunction, chronic cerebrospinal fluid leak, cochlear implants, and people who are experiencing homelessness, live in settings experiencing sustained high IPD rates, or who are in residential care, including long-term care homes; adults 50 years of age and older with chronic heart or lung disease, chronic neurologic conditions that impair clearance of oral secretions, diabetes mellitus, who smoke, with substance use disorders or with an alcohol use disorder, should receive Pneu-C-20; adults 18 to 49 years of age with chronic heart or lung disease, chronic neurologic conditions that impair clearance of oral secretions, diabetes mellitus, who smoke, with substance use disorders or with an alcohol use disorder, may be offered Pneu-C-15 or Pneu-C-20 at clinical discretion. - 1 dose of Pneu-C-20 vaccine is recommended, Pneu-C-15 followed by Pneu-P-23 may be offered as an alternative.

Table 7 - Footnote E

Meningococcal conjugate quadrivalent: in previously unimmunized adults at high risk of invasive meningococcal disease (IMD) - 2 doses, 8 weeks apart. In previously immunized adults -booster dose every 3 to 5 years if last vaccinated at 6 years of age and younger and every 5 years for those last vaccinated at 7 years of age and older.

Table 7 - Footnote F

Multicomponent meningococcal (4CMenB): adults at high risk of IMD should be considered for immunization - 2 doses of 4CMenB vaccine, at least 4 weeks apart.

Table 7 - Footnote G

Hepatitis A: adults in high risk groups - 2 doses, 6-36 months apart (depending on product used).

Table 7 - Footnote H

Hepatitis B (HB): adults in high risk groups - 3 or 4 dose schedule (depending on product used). Higher dose of monovalent HB vaccine recommended for those with certain immunocompromising conditions, chronic renal failure and dialysis.

Table 7 - Footnote I

Hepatitis A-hepatitis B: adults without chronic renal failure and immunocompromising conditions: combined vaccine preferred if both hepatitis A and standard dosage hepatitis B vaccines are recommended - 3 or 4 dose schedule.

Table 7 - Footnote J

Influenza: recommended for all adults, with focus on adults at high risk of influenza-related complications - 1 dose annually.

Table 7 - Footnote K

Typhoid: adults with ongoing or intimate exposure to a chronic carrier of Salmonella typhi - 1 dose injectable typhoid vaccine or 4 doses oral typhoid vaccine; re-immunization recommended if at continuing risk.

Table 7 - Footnote L

Rabies: adults at high risk of close contact with rabid animals - 3 doses for pre-exposure immunization. Periodic serologic testing and booster doses (if required) for those at continuing high risk.

Table 7 - Footnote M

Varicella: adults 18 to less than 50 years of age without history of VZV infection (self-reported or diagnosed by a health care provider), documented evidence of immunization with 2 doses of a varicella-containing vaccine or laboratory evidence of immunity - 2 doses. Self-reported history or health care provider diagnosis is not considered a reliable correlate of immunity for pregnant women with significant exposure to varicella zoster virus, immunocompromised individuals and health care workers who are newly hired into the Canadian health care system.

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